ADAMTSL-1 Antibody

ADAMTS-like protein 1 ADAMTSL-1) is a secreted molecule resembling members of the ADAMTS family of proteases. Punctin lacks the pro-metalloprotease and the disintegrin-like domain typical of this family but contains other ADAMTS domains in precise order including four thrombospondin type I repeats. In transfected COS-1 cells, ADAMTSL-1 is deposited in the cell substratum in a punctate fashion and is excluded from focal contacts. ADMTSL-1 is a member of ADAMTS-like proteins that have important functions in the extracellular matrix.