Actin Reorganization Antibody Sampler Kit
- 貨號 Cat. No.
- 9967T
- 規格 Size
- 1 Kit
- 品牌 Brand
- Cell Signaling Technology
Description
Product Description
The Actin Reorganization Antibody Sampler Kit contains reagents to examine proteins that help regulate the dynamic actin cytoskeleton. This kit includes enough primary and secondary antibodies to perform two Western blot experiments with each primary antibody.
Specificity / Sensitivity
All activation state antibodies only detect their target proteins when modified at the indicated site. Cofilin (D3F9) XP® Rabbit mAb detects endogenous levels of total cofilin protein. VASP (9A2) Rabbit mAb detects endogenous levels of total VASP protein. Neither of the Ezrin/Radixin/Moesin antibodies cross-react with related phosphoproteins such as merlin or band 4.1.
Source / Purification
Monoclonal antibodies are produced by immunizing animals with synthetic peptides corresponding to central residues of human cofilin1 and residues near the carboxy terminus of human and mouse VASP. Monoclonal antibodies are produced by immunizing animals with synthetic phosphopeptides corresponding to residues surrounding Ser3 of human cofilin and Thr567 of human ezrin. Activation state polyclonal antibodies are produced by immunizing rabbits with synthetic phosphopeptides corresponding to residues surrounding Ser157 and Ser239 of human VASP. Polyclonal antibodies are purified by protein A and peptide affinity chromatography.
