ACK-1 Antibody

Catalog Number

251595

Unit

0.1mg

Isotype

Applications

Species reactivity

Format

Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Description

ACK-1 (Activated CDC42 kinase 1) is a tyrosine kinase which mediates CDC42-dependent cell migration via phosphorylation of BCAR1. ACK-1 binds to both poly- and mono-ubiquitin and regulates ligand-induced degradation of EGFR. ACK-1 also participates in clathrin-mediated endocytosis.

Alternate Names

ACK-1; Activated CDC42 kinase 1; Tyrosine kinase non-receptor protein 2; TNK2; ACK1

Accession No.

Q07912

 

Antigen

KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human ACK-1.

Application Notes

E: 1:500-1:1,000

WB: 1:100-1:500

IHC: 1:100-1:500

Storage

Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.