Acetylcholinesterase Activity Colorimetric Assay Kit

Alternate Name : AChE Activity Colorimetric Assay Kit, Acetylhydrolase Activity Colorimetric Assay Kit

Tag Line :

Highly Sensitive Assay

Storage Conditions: -20°C

Shelf life: 12 months

Summary :

• Detection: Absorbance (OD 570 nm)
• Application:
- Measurement of AChE activity in various tissues/cells
- Screening of AChE inhibitors

Detection Method: Absorbance (OD 570 nm)

Features & Benefits:

• Rapid, simple & convenient
• This assay kit can detect acetylcholinesterase activity as low as 0.5 mU/ml in a variety of samples

Description:

Acetylcholinesterase (AChE) is one of the most crucial enzymes associated with nerve response and function. AChE is a serine protease that hydrolyzes the neurotransmitter acetylcholine. Irreversible inhibition of AChE may lead to muscular paralysis, convulsions, bronchial constriction, and death by asphyxiation. BioVision’s Acetylcholinesterase Activity Assay Kit provides a simple and sensitive method for continuous monitoring of enzymatic activity using colorimetry (OD 570 nm). In this assay, AChE converts acetylcholine substrate to choline, which is then oxidized by choline oxidase (CO) to produce an intermediate. The intermediate reacts with a highly specific probe to generate color. This assay kit can detect acetylcholinesterase activity as low as 0.5 mU/ml in a variety of samples.