Acetylcholinesterase (12B4) Antibody

Acetylcholinesterase (AChE, EC.3.1.1.7.) is an enzyme located in the postsynaptic membrane and in the muscle endplates, where it hydrolyses the neurotransmitter acetylcholin. AChE from brain is a tetramer (G4-AChE) with a molecular mass of 320 kDa, AChE from erythrocytes is a dimer (G2-AChE) with a molecular mass of 170 kDa. This antibody is specific for human acetylcholinesterase. No cross-reaction is seen with human BtChE and AChE from flounder or Torpedo marmorata.