Ac-Leu-Leu-Nle-CHO (MG-101)

貨號 Cat. No.
I-160
規格 Size
5 mg
品牌 Brand
Boston Biochem

Description

Ac-Leu-Leu-Nle-CHO (MG-101)

Catalog #: I-160




Ac-Leu-Leu-Nle-CHO (MG-101)






Product Source: 

Synthetic



Peptide aldehydes form a covalent hemiacetal adduct with the 20S proteasome, inhibiting the chymotrypsin-like peptidase activity. These inhibitors are reversible and cell-permeable, and also inhibit the activity of calpains and cathepsins.


Product Information



Quantity: 

5 mg




Structure: 








Purity: 

> 95% by TLC, HPLC. Structure confirmed by NMR.






Solubility: 

Pellet dry compound prior to DMSO addition. Soluble up to 15 mg/ml.




 


Use & Storage



Use: 

Add from DMSO stock directly to in vitro or in vivo assay at desired concentration. Pre-incubation with compound prior to assay is recommended for maximal effect. 20S proteasome Ki = 2 μM






Storage: 

Store DMSO stock at -20°C. Avoid multiple freeze/thaw cycles.



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