ABT-888
- 貨號 Cat. No.
- 1620-1
- 規格 Size
- 1 mg
Description
1 mg. Purity >99%. CAS# 912445-05-7 . Potent inhibitor of PARP-1 and PARP-2 (potency ≤5 nM in vitro). Does not inhibit other NAD-binding enzymes. Has minimal CYP450 inhibition and induction. Shows broad spectrum of chemo- and radio-potentiation. Does not show inherent cytotoxicity and shows no single agent activity in tumor models. Soluble in water or DMSO. Store cool and dry at -20C. Protect from light.