ABCB11 Antibody (LS-B2170)

貨號 Cat. No.: LS-B2170
規格 Size: 50 Âµg
品牌 Brand: LSBio

Description

Antibody Catalog ID:	LS-B2170
Antibody Validation:	This antibody replaces catalog number LS-C4240. It has been validated for use in the following assays: IHC-P.
Antibody Target:	ATP-Binding Cassette, Sub-Family B (Mdr/Tap), Member 11 ABCB11)
Synonyms:	ABCB11, ABC16, Abcb11, ATP-binding cassette sub-family B (MDR/TAP) member 11, bile salt export pump, BSEP, PFIC-2, PFIC2, PGY4, progressive familial intrahepatic cholestasis 2, sister of P-glycoprotein, SPGP
Family:	Transporter
Subfamily:	ATP-binding cassette - ABCB/MDR
Host:	ABCB11 antibody was produced in Mouse
Antigen Species:	ABCB11 antibody was raised against Human
Clonality:	Monoclonal
Isotype:	IgG1
Antigen Type:	Synthetic peptide
Immunogen:	ABCB11 antibody was raised against synthetic peptide corresponding to aa 705-718 (Y705LVHEPPLAVVDHK718) of human BSEP (bile salt export pump).
Antibody Specificity:	Recognizes human BSEP. Does not cross-react with human P-glycoprotein.
Antigen Modification:	aa705-718
Purification:	Protein G Column
Presentation:	0.7% BSA, 100nM sodium azide, before the addition of glycerol to 40%
Recommended Storage:	Long term: -20°C; Short term: +4°C
Antibody Usage Summary:	Immunohistochemistry: LS-B2170 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody LS-D2, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B2170 was determined to be 5 ug/ml.
Antibody Uses:	Immunohistochemistry - Paraffin (IHC-P) (5 µg/ml), Immunocytochemistry (ICC), Western blot (WB) (Optimal dilution to be determined by the researcher)
Size:	50 µg
Concentration:	0.5 mg/ml