A-ACTININ MONOCLONAL ANTIBODY
Antibodies
- 貨號 Cat. No.
- E-AB-22127
- 規格 Size
- 20μL、60μL、120μL、200μL
- 品牌 Brand
- Iwai North America
- Reactivity
- Human 、 Mouse
Description
Image 1
Image 1
A-ACTININ MONOCLONAL ANTIBODY
PRICE:
$69.00
SKU:
E-AB-22127-20
SHIPPING:
Calculated at checkout
* SIZE:
20ul 60ul 120ul 200ul
QUANTITY
ADD TO WISHLIST
SHARE
PRODUCT DESCRIPTION
Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
a-actinin Monoclonal Antibody E-AB-22127 1D4 IgG IHC-p* Human,Mouse,Rat 20μL, 60μL, 120μL, 200μL
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
Image 1
A-ACTININ MONOCLONAL ANTIBODY
PRICE:
$69.00
SKU:
E-AB-22127-20
SHIPPING:
Calculated at checkout
* SIZE:
20ul 60ul 120ul 200ul
QUANTITY
ADD TO WISHLIST
SHARE
PRODUCT DESCRIPTION
Product Name Cat# Clone# Isotype Applications Reactivity Unit/Size
a-actinin Monoclonal Antibody E-AB-22127 1D4 IgG IHC-p* Human,Mouse,Rat 20μL, 60μL, 120μL, 200μL
Description
Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, cytoskeletal, alpha actinin isoform and maps to the same site as the structurally similar erythroid beta spectrin gene. Three transcript variants encoding different isoforms have been found for this gene.
