5-Lipoxygenase Inhibitor Screening Kit (Fluorometric)

Alternate Name :

Tag Line :

Highly Sensitive; Includes recombinant Zileuton as inhibitor control

Storage Conditions: -20°C

Shelf life: 12 months

Summary :

• Detection method- Fluorescence (Ex/Em 500/536 nm)
• Species reactivity- Human
• Applications -Screening of potential inhibitors of 5-lipoxygenase

Detection Method: Fluorescence (Ex/Em 500/536 nm)

Features & Benefits:

• Simple procedure; takes only ~40 min
• Fast and convenient

Description:

5-Lipoxygenase (5-LOX) is a non-heme iron-containing dioxygenase that converts unsaturated fatty acids to epoxides; for example the synthesis of leukotrienes from arachidonic acid. It is involved in processes like cell proliferation, differentiation and inflammation and has been implicated in inflammation and hyper proliferation mediated diseases like asthma, rheumatoid arthritis and cancer. Research for identifying potential remedies for such diseases involves the identification of inhibitors of 5-lipoxygenase. BioVision’s 5-Lipoxygenase Inhibitor Screening Kit uses Zileuton, a well-known 5-lipoxygenase inhibitor as positive control, and provides a simple and fast method to screen/ characterize potential 5-lipoxygenase inhibitors