20S Immunoproteasome
- 貨號 Cat. No.
- E-376
- 規格 Size
- 50 μg
- 品牌 Brand
- Boston Biochem
Description
20S Immunoproteasome
mouse
Product Information
50 μg
X mg/ml (X μM) in 50 mM HEPES pH 7.6, 100mM NaCl, 1mM DTT. Actual concentration will vary with specific Lot #.
700 kDa
> 95% by SDS-PAGE
Use & Storage
Typical enzyme concentration for assay is 0.1-1 nM. 20S can be activated by SDS (0.035%) or with PA28 Activator (Cat. # E-380).
Store at -80°C. Avoid multiple freeze/thaw cycles.
Catalog #: E-376
20S Immunoproteasome
Product Source:
mouse
The 20S catalytic core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Immunoproteasomes are modified forms of the constitutive 20S that function in MHC Class I antigen processing. During immunoproteasome assembly, the constitutive catalytic subunits (Delta, Z and X) are replaced by the inducible subunits LMP2, LMP7 and MECL, the former two being encoded by MHC. This protein has been purified from mouse spleen.
Product Information
Quantity:
50 μg
Stock:
X mg/ml (X μM) in 50 mM HEPES pH 7.6, 100mM NaCl, 1mM DTT. Actual concentration will vary with specific Lot #.
MW:
700 kDa
Purity:
> 95% by SDS-PAGE
Use & Storage
Use:
Typical enzyme concentration for assay is 0.1-1 nM. 20S can be activated by SDS (0.035%) or with PA28 Activator (Cat. # E-380).
Storage:
Store at -80°C. Avoid multiple freeze/thaw cycles.