17-Hydroxyprogesterone ELISA Kit

Kits

貨號 Cat. No.
E4345-100
規格 Size
E4345-100
Reactivity
Universal
Sample Type
and tissue 、 extracted dried fecal samples 、 Extracted serum and plasma 、 or in urine

Description




Alternate Name :


 

Tag Line :


A competitive ELISA kit for the quantitative measurement of 17-Hydroxyprogesterone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue


 

Storage Conditions: 4°C


 

Shelf life: 6 months


 

Summary :


• Detection method- Absorbance (450 nm)
• Species reactivity- Universal
• Application- quantitative measurement of human total 17-HOP in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue


 

Detection Method: Absorbance (450 nm)


 

Features & Benefits:


Easy, convenient and time-saving method to measure the level of 17-HOP in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue.
Detection Range: 6000 – 24.69 pg/ml
Sensitivity: < 20.3 pg/ml
Detection Limit: 15.4 pg/ml


 

Description:


The adrenal glands, ovaries, testes, and placenta produce 17-hydroxyprogesterone. It is hydroxylated at the 11 and 21 position to produce cortisol. Deficiency of either 11- or 21-hydroxylase results in decreased cortisol synthesis, and feedback inhibition of adrenocorticotropic hormone (ACTH) secretion is lost. Consequent increased pituitary release of ACTH will increase production of 17-HOP. But, if 17-alpha-hydroxylase (which allows formation of 17-HOP from progesterone) or 3ß-hydroxysteroid dehydrogenase type 2 (which allows formation of 17-hydroxyprogesterone formation from 17-hydroxypregnenolone) are deficient, 17-HOP levels are low with possible increase in progesterone or pregnenolone respectively. BioVision’s 17-Hydroxyprogesterone ELISA kit is a competitive ELISA assay for the quantitative measurement of 17-Hydroxyprogesterone in extracted serum and plasma, or in urine, extracted dried fecal samples, and tissue culture media samples.


 





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