14-3-3 Monoclonal Antibody
- 貨號 Cat. No.
- 3126-100
- 規格 Size
- 100 ug
Description
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pbISOTYPE: /bMouse IgG/p
pbCLONE: /bS22G SPECIES: human, mouse, rat, pig, monkey, rabbit, dog, sheep, bovine/p
pbANTIBODY FORMULATION: /b100 ug (0.5 mg/ml) immunoaffinity purified mouse monoclonal antibody in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid repeated freeze/defrost cycles. DESCRIPTION: The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. The family of proteins is present in particularly high concentrations in mammalian brain and may be involved in the regulation of neuronal activity. The 14-3-3 proteins exist as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. APPLICATIONS: The antibody can be used for Western blotting (1-2 ug/ml) and immunohistochemistry (20-40 ug/ml). However, the optimal conditions should be determined individually./p
pbSPECIFICITY: /bThe antibody recognizes a ~31 kDa protein, corresponding to the apparent molecular weight of the ß and ? isoforms of 14-3-3 on SDS-PAGE immunoblots. NOTE: For Research Use Only! Not to be used in human./p
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pbISOTYPE: /bMouse IgG/p
pbCLONE: /bS22G SPECIES: human, mouse, rat, pig, monkey, rabbit, dog, sheep, bovine/p
pbANTIBODY FORMULATION: /b100 ug (0.5 mg/ml) immunoaffinity purified mouse monoclonal antibody in PBS containing 1 mg/ml BSA and 1.5 mM sodium azide and 50% glycerol./p
pbSTORAGE CONDITIONS: /bStore at -20oC. For long term storage, aliquot and refreeze at -70oC. Avoid repeated freeze/defrost cycles. DESCRIPTION: The 14-3-3 proteins comprise a family of highly conserved acidic proteins which play a role in both signal transduction and the cell cycle by binding to and regulating several different proteins. The family of proteins is present in particularly high concentrations in mammalian brain and may be involved in the regulation of neuronal activity. The 14-3-3 proteins exist as either homo- or heterodimers which interact via their N-terminal domains and are subject to phosphorylation by protein kinase C. APPLICATIONS: The antibody can be used for Western blotting (1-2 ug/ml) and immunohistochemistry (20-40 ug/ml). However, the optimal conditions should be determined individually./p
pbSPECIFICITY: /bThe antibody recognizes a ~31 kDa protein, corresponding to the apparent molecular weight of the ß and ? isoforms of 14-3-3 on SDS-PAGE immunoblots. NOTE: For Research Use Only! Not to be used in human./p
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