| Multiple GMP Grade Products Facilitate Standardization and Large-Scale Production of Mesenchymal Stem Cells |
|
| Hello,
Our newly launched MSC Solutinos in this week's digest, including:
· Challenges in Standardization and Scaling Up Mesenchymal Stem Cells Production
· Newly launched: GMP Recombinant Human Fibronectin
· Validation Data
Keep reading to learn more! |
|
|
Stem cells, known as "universal cells," can self-replicate and differentiate. Mesenchymal stem cells (MSCs), leading stem cell therapy with 655 global projects, face challenges in large-scale production. The adhesion and diffusion of MSCs in culture depend heavily on the extracellular matrix, with fibronectin playing a key role in differentiation and tissue formation.
Our newly launched GMP Recombinant Human Fibronectin is specifically designed to facilitate the efficient and large-scale production of MSCs in vitro. In addition, we have developed a series of GMP grade growth factors and cytokine detection kits, which can fully support the cultivation and quality control related research of MSCs! |
|
|
· E coli. recombinant protein expression, not human plasma (avoid safety risks)
· Lot to lot consistency and large manufacturing supply
· High bioactivity verified in the application
|
|
|
|
GMP Fibronectin (GMP-FINH18) could promote mesenchymal stem cell attachment and proliferation in several passages, comparable with Competitor T. The bioactivity of GMP Fibronectin (GMP-FINH18) is similar with PG Fibronectin (FIN-H5116).
|
|
GMP Fibronectin (GMP-FINH18) could maintain the stemness of MSC in several passages, with high expression of MSC markers CD73, CD90 and CD105 and negative expression of HLA-DR, CD34 and CD45. The stemness ability is comparable with Competitor T and similar with PG Fibronectin (FIN-H5116).
|
|
|
|
|